Discrepancies in current practice of pathological evaluation of sentinel lymph nodes in breast cancer. Results of a questionnaire based survey by the European Working Group for Breast Screening Pathology
Identifieur interne : 000599 ( France/Analysis ); précédent : 000598; suivant : 000600Discrepancies in current practice of pathological evaluation of sentinel lymph nodes in breast cancer. Results of a questionnaire based survey by the European Working Group for Breast Screening Pathology
Auteurs : G. Cserni [Hongrie] ; I. Amendoeira [Portugal] ; N. Apostolikas [Grèce] ; J P Bellocq [France] ; S. Bianchi [Italie] ; W. Boecker [Allemagne] ; B. Borisch [Suisse] ; C E Connolly [Irlande (pays)] ; T. Decker [Allemagne] ; P. Dervan [Irlande (pays)] ; M. Drijkoningen [Belgique] ; I O Ellis [Royaume-Uni] ; C W Elston [Royaume-Uni] ; V. Eusebi [Italie] ; D. Faverly [Belgique] ; P. Heikkila [Finlande] ; R. Holland [Pays-Bas] ; H. Kerner [Israël] ; J. Kulka [Hongrie] ; J. Jacquemier [France] ; M. Lacerda [Portugal] ; J. Martinez-Penuela [Espagne] ; C. De Miguel [Espagne] ; J L Peterse [Pays-Bas] ; F. Rank [Danemark] ; P. Regitnig [Autriche] ; A. Reiner [Autriche] ; A. Sapino [Italie] ; B. Sigal-Zafrani [France] ; A M Tanous [Luxembourg (pays)] ; S. Thorstenson [Suède] ; E. Zozaya [Espagne] ; G. Fejes [Hongrie] ; C A Wells [Royaume-Uni]Source :
- Journal of Clinical Pathology [ 0021-9746 ] ; 2004-07.
English descriptors
- KwdEn :
- CK, cytokeratin, EIO, European Institute of Oncology, EWGBSP, European working group for breast screening pathology, HE, haematoxylin and eosin, IHC, immunohistochemistry, ITC, isolated tumour cell, RT-PCR, reverse transcriptase polymerase chain reaction, SLN, sentinel lymph node, SLNB, sentinel lymph node biopsy, breast cancer, guidelines, questionnaire, sentinel lymph nodes.
Abstract
Aims: To evaluate aspects of the current practice of sentinel lymph node (SLN) pathology in breast cancer via a questionnaire based survey, to recognise major issues that the European guidelines for mammography screening should address in the next revision. Methods: A questionnaire was circulated by mail or electronically by the authors in their respective countries. Replies from pathology units dealing with SLN specimens were evaluated further. Results: Of the 382 respondents, 240 European pathology units were dealing with SLN specimens. Sixty per cent of these units carried out intraoperative assessment, most commonly consisting of frozen sections. Most units slice larger SLNs into pieces and only 12% assess these slices on a single haematoxylin and eosin (HE) stained slide. Seventy one per cent of the units routinely use immunohistochemistry in all cases negative by HE. The terms micrometastasis, submicrometastasis, and isolated tumour cells (ITCs) are used in 93%, 22%, and 71% of units, respectively, but have a rather heterogeneous interpretation. Molecular SLN staging was reported by only 10 units (4%). Most institutions have their own guidelines for SLN processing, but some countries also have well recognised national guidelines. Conclusions: Pathological examination of SLNs throughout Europe varies considerably and is not standardised. The European guidelines should focus on standardising examination. They should recommend techniques that identify metastases > 2 mm as a minimum standard. Uniform reporting of additional findings may also be important, because micrometastases and ITCs may in the future be shown to have clinical relevance.
Url:
DOI: 10.1136/jcp.2003.013599
Affiliations:
- Allemagne, Autriche, Belgique, Danemark, Espagne, Finlande, France, Grèce, Hongrie, Irlande (pays), Israël, Italie, Luxembourg (pays), Pays-Bas, Portugal, Royaume-Uni, Suisse, Suède
- Alsace (région administrative), Berlin, Grand Est, Hovedstaden, Piémont, Provence-Alpes-Côte d'Azur, Province du Brabant flamand, Uusimaa, Vienne (Autriche), Émilie-Romagne, Île-de-France
- Berlin, Bologne, Copenhague, Helsinki, Louvain, Marseille, Paris, Strasbourg, Turin, Vienne (Autriche)
- Université d'Helsinki, Université de Bologne
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ISTEX:B226F51399088E13C5EB6CF2F70CA050F14F8191Le document en format XML
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Results of a questionnaire based survey by the European Working Group for Breast Screening Pathology</title><author><name sortKey="Cserni, G" sort="Cserni, G" uniqKey="Cserni G" first="G" last="Cserni">G. Cserni</name><affiliation wicri:level="1"><country xml:lang="fr">Hongrie</country><wicri:regionArea>Department of Pathology, Bács-Kiskun County Teaching Hospital, H-6000 Kecskemét</wicri:regionArea><wicri:noRegion>H-6000 Kecskemét</wicri:noRegion></affiliation></author><author><name sortKey="Amendoeira, I" sort="Amendoeira, I" uniqKey="Amendoeira I" first="I" last="Amendoeira">I. Amendoeira</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Instituto de Patologia et Imunologia Molecular da Universidade do Porto e Serviço de Anatomia Patologica, Hospital S Joaõ, 4200 Porto</wicri:regionArea><wicri:noRegion>4200 Porto</wicri:noRegion></affiliation></author><author><name sortKey="Apostolikas, N" sort="Apostolikas, N" uniqKey="Apostolikas N" first="N" last="Apostolikas">N. Apostolikas</name><affiliation wicri:level="1"><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Pathology, Saint Savas Hospital, 115 22 Athens</wicri:regionArea><wicri:noRegion>115 22 Athens</wicri:noRegion></affiliation></author><author><name sortKey="Bellocq, J P" sort="Bellocq, J P" uniqKey="Bellocq J" first="J P" last="Bellocq">J P Bellocq</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Service d’Anatomie Pathologique, Hopital de Hautepierre, F-67098 Strasbourg</wicri:regionArea><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Bianchi, S" sort="Bianchi, S" uniqKey="Bianchi S" first="S" last="Bianchi">S. Bianchi</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Human Pathology and Oncology, University of 50134 Florence</wicri:regionArea><wicri:noRegion>University of 50134 Florence</wicri:noRegion></affiliation></author><author><name sortKey="Boecker, W" sort="Boecker, W" uniqKey="Boecker W" first="W" last="Boecker">W. Boecker</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gerhard-Domagk Institut fur Pathologie, Universitat von Munster, D-48129 Munster</wicri:regionArea><wicri:noRegion>48129 Munster</wicri:noRegion><wicri:noRegion>D-48129 Munster</wicri:noRegion></affiliation></author><author><name sortKey="Borisch, B" sort="Borisch, B" uniqKey="Borisch B" first="B" last="Borisch">B. Borisch</name><affiliation wicri:level="1"><country xml:lang="fr">Suisse</country><wicri:regionArea>Centre Médicale Universitaire, 1211 Genève</wicri:regionArea><wicri:noRegion>1211 Genève</wicri:noRegion></affiliation></author><author><name sortKey="Connolly, C E" sort="Connolly, C E" uniqKey="Connolly C" first="C E" last="Connolly">C E Connolly</name><affiliation wicri:level="1"><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Pathology, Clinical Sciences Institute, University College Hospital, Galway</wicri:regionArea><wicri:noRegion>Galway</wicri:noRegion></affiliation></author><author><name sortKey="Decker, T" sort="Decker, T" uniqKey="Decker T" first="T" last="Decker">T. Decker</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pathology, The Breast Unit, HELIOS Medical Centre, D-13125 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Dervan, P" sort="Dervan, P" uniqKey="Dervan P" first="P" last="Dervan">P. Dervan</name><affiliation wicri:level="1"><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Pathology Department, Mater Hospital, University College Dublin 7</wicri:regionArea><wicri:noRegion>University College Dublin 7</wicri:noRegion></affiliation></author><author><name sortKey="Drijkoningen, M" sort="Drijkoningen, M" uniqKey="Drijkoningen M" first="M" last="Drijkoningen">M. Drijkoningen</name><affiliation wicri:level="3"><country xml:lang="fr">Belgique</country><wicri:regionArea>Pathologische Ontleedkunde, University Hospital, 3000 Leuven</wicri:regionArea><placeName><region type="province" nuts="2">Province du Brabant flamand</region><settlement type="city">Louvain</settlement></placeName></affiliation></author><author><name sortKey="Ellis, I O" sort="Ellis, I O" uniqKey="Ellis I" first="I O" last="Ellis">I O Ellis</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Histopathology, City Hospital, Nottingham NG5 1PB</wicri:regionArea><wicri:noRegion>Nottingham NG5 1PB</wicri:noRegion></affiliation></author><author><name sortKey="Elston, C W" sort="Elston, C W" uniqKey="Elston C" first="C W" last="Elston">C W Elston</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Histopathology, City Hospital, Nottingham NG5 1PB</wicri:regionArea><wicri:noRegion>Nottingham NG5 1PB</wicri:noRegion></affiliation></author><author><name sortKey="Eusebi, V" sort="Eusebi, V" uniqKey="Eusebi V" first="V" last="Eusebi">V. Eusebi</name><affiliation wicri:level="4"><country xml:lang="fr">Italie</country><wicri:regionArea>Sezione Anatomia Patologica M. Malpighi, Universita di Bologna, Ospedale Bellaria, 40139 Bologna</wicri:regionArea><orgName type="university">Université de Bologne</orgName><placeName><settlement type="city">Bologne</settlement><region nuts="2" type="region">Émilie-Romagne</region></placeName></affiliation></author><author><name sortKey="Faverly, D" sort="Faverly, D" uniqKey="Faverly D" first="D" last="Faverly">D. Faverly</name><affiliation wicri:level="3"><country xml:lang="fr">Belgique</country><wicri:regionArea>CMP Laboratory, 1070 Bruxelles</wicri:regionArea><placeName><region type="land" nuts="2">Vienne (Autriche)</region><settlement type="city">Vienne (Autriche)</settlement></placeName></affiliation></author><author><name sortKey="Heikkila, P" sort="Heikkila, P" uniqKey="Heikkila P" first="P" last="Heikkila">P. Heikkila</name><affiliation wicri:level="4"><country xml:lang="fr">Finlande</country><wicri:regionArea>Haartman Institute, University of Helsinki, FIN 00014 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Holland, R" sort="Holland, R" uniqKey="Holland R" first="R" last="Holland">R. Holland</name><affiliation wicri:level="1"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>National Expert & Training Centre for Breast Cancer Screening, Academisch Ziekenhuis Nijmegen, 6500 HB Nijmegen</wicri:regionArea><wicri:noRegion>6500 HB Nijmegen</wicri:noRegion></affiliation></author><author><name sortKey="Kerner, H" sort="Kerner, H" uniqKey="Kerner H" first="H" last="Kerner">H. Kerner</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Pathology, Rambam Hospital, 31096 Haifa</wicri:regionArea><wicri:noRegion>31096 Haifa</wicri:noRegion></affiliation></author><author><name sortKey="Kulka, J" sort="Kulka, J" uniqKey="Kulka J" first="J" last="Kulka">J. Kulka</name><affiliation wicri:level="1"><country xml:lang="fr">Hongrie</country><wicri:regionArea>2nd Department of Pathology, Semmelweis University, H-1091 Budapest</wicri:regionArea><wicri:noRegion>H-1091 Budapest</wicri:noRegion></affiliation></author><author><name sortKey="Jacquemier, J" sort="Jacquemier, J" uniqKey="Jacquemier J" first="J" last="Jacquemier">J. Jacquemier</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Institut Paoli Calmettes, 13273 Marseille</wicri:regionArea><placeName><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Lacerda, M" sort="Lacerda, M" uniqKey="Lacerda M" first="M" last="Lacerda">M. Lacerda</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Laboratorio De Histopatologica, Centro Regional De Oncologia De Coimbra, 3000 Coimbra</wicri:regionArea><wicri:noRegion>3000 Coimbra</wicri:noRegion></affiliation></author><author><name sortKey="Martinez Penuela, J" sort="Martinez Penuela, J" uniqKey="Martinez Penuela J" first="J" last="Martinez-Penuela">J. Martinez-Penuela</name><affiliation wicri:level="1"><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Pathology, Hospital de Navarra, 31008 Pamplona</wicri:regionArea><wicri:noRegion>31008 Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="De Miguel, C" sort="De Miguel, C" uniqKey="De Miguel C" first="C" last="De Miguel">C. De Miguel</name><affiliation wicri:level="1"><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Pathology, Hospital Virgen del Camino, 31008 Pamplona</wicri:regionArea><wicri:noRegion>31008 Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Peterse, J L" sort="Peterse, J L" uniqKey="Peterse J" first="J L" last="Peterse">J L Peterse</name><affiliation wicri:level="1"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pathology, The Netherlands Cancer Institute, 1066 CX Amsterdam</wicri:regionArea><wicri:noRegion>1066 CX Amsterdam</wicri:noRegion></affiliation></author><author><name sortKey="Rank, F" sort="Rank, F" uniqKey="Rank F" first="F" last="Rank">F. Rank</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Center of Laboratory Medicine and Pathology, Department of Pathology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Regitnig, P" sort="Regitnig, P" uniqKey="Regitnig P" first="P" last="Regitnig">P. Regitnig</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Institut fur Pathologie der Karl-Franzens Universitat Graz, A-8036 Graz</wicri:regionArea><wicri:noRegion>A-8036 Graz</wicri:noRegion></affiliation></author><author><name sortKey="Reiner, A" sort="Reiner, A" uniqKey="Reiner A" first="A" last="Reiner">A. Reiner</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute of Pathology, Donauspital, A-1220 Wien</wicri:regionArea><wicri:noRegion>A-1220 Wien</wicri:noRegion></affiliation></author><author><name sortKey="Sapino, A" sort="Sapino, A" uniqKey="Sapino A" first="A" last="Sapino">A. Sapino</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Biological Science and Human Oncology, University of Turin, 10126 Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Sigal Zafrani, B" sort="Sigal Zafrani, B" uniqKey="Sigal Zafrani B" first="B" last="Sigal-Zafrani">B. Sigal-Zafrani</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Institut Curie, Section Medicale et Hospitaliere, 75231 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Tanous, A M" sort="Tanous, A M" uniqKey="Tanous A" first="A M" last="Tanous">A M Tanous</name><affiliation wicri:level="1"><country xml:lang="fr">Luxembourg (pays)</country><wicri:regionArea>Division d’Anatomie Pathologique, Laboratoire National de Santé</wicri:regionArea><wicri:noRegion>Laboratoire National de Santé</wicri:noRegion></affiliation></author><author><name sortKey="Thorstenson, S" sort="Thorstenson, S" uniqKey="Thorstenson S" first="S" last="Thorstenson">S. Thorstenson</name><affiliation wicri:level="1"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Pathology and Cytology, Kalmar Hospital, S-391 85 Kalmar</wicri:regionArea><wicri:noRegion>S-391 85 Kalmar</wicri:noRegion></affiliation></author><author><name sortKey="Zozaya, E" sort="Zozaya, E" uniqKey="Zozaya E" first="E" last="Zozaya">E. Zozaya</name><affiliation wicri:level="1"><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Pathology, Hospital de Navarra, 31008 Pamplona</wicri:regionArea><wicri:noRegion>31008 Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Fejes, G" sort="Fejes, G" uniqKey="Fejes G" first="G" last="Fejes">G. Fejes</name><affiliation wicri:level="1"><country xml:lang="fr">Hongrie</country><wicri:regionArea>Department of Informatics, Bács-Kiskun County Teaching Hospital, H-6000 Kecskemét</wicri:regionArea><wicri:noRegion>H-6000 Kecskemét</wicri:noRegion></affiliation></author><author><name sortKey="Wells, C A" sort="Wells, C A" uniqKey="Wells C" first="C A" last="Wells">C A Wells</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Histopathology, St Bartholomew’s Hospital Medical School, London EC1A 7BE</wicri:regionArea><wicri:noRegion>London EC1A 7BE</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Clinical Pathology</title><title level="j" type="abbrev">J Clin Pathol</title><idno type="ISSN">0021-9746</idno><idno type="eISSN">1472-4146</idno><imprint><publisher>BMJ Publishing Group Ltd and Association of Clinical Pathologists</publisher><date type="published" when="2004-07">2004-07</date><biblScope unit="volume">57</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="695">695</biblScope></imprint><idno type="ISSN">0021-9746</idno></series><idno type="istex">B226F51399088E13C5EB6CF2F70CA050F14F8191</idno><idno type="DOI">10.1136/jcp.2003.013599</idno><idno type="href">jclinpath-57-695.pdf</idno><idno type="PMID">15220360</idno><idno type="local">0570695</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0021-9746</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>CK, cytokeratin</term><term>EIO, European Institute of Oncology</term><term>EWGBSP, European working group for breast screening pathology</term><term>HE, haematoxylin and eosin</term><term>IHC, immunohistochemistry</term><term>ITC, isolated tumour cell</term><term>RT-PCR, reverse transcriptase polymerase chain reaction</term><term>SLN, sentinel lymph node</term><term>SLNB, sentinel lymph node biopsy</term><term>breast cancer</term><term>guidelines</term><term>questionnaire</term><term>sentinel lymph nodes</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Aims: To evaluate aspects of the current practice of sentinel lymph node (SLN) pathology in breast cancer via a questionnaire based survey, to recognise major issues that the European guidelines for mammography screening should address in the next revision. Methods: A questionnaire was circulated by mail or electronically by the authors in their respective countries. Replies from pathology units dealing with SLN specimens were evaluated further. Results: Of the 382 respondents, 240 European pathology units were dealing with SLN specimens. Sixty per cent of these units carried out intraoperative assessment, most commonly consisting of frozen sections. Most units slice larger SLNs into pieces and only 12% assess these slices on a single haematoxylin and eosin (HE) stained slide. Seventy one per cent of the units routinely use immunohistochemistry in all cases negative by HE. The terms micrometastasis, submicrometastasis, and isolated tumour cells (ITCs) are used in 93%, 22%, and 71% of units, respectively, but have a rather heterogeneous interpretation. Molecular SLN staging was reported by only 10 units (4%). Most institutions have their own guidelines for SLN processing, but some countries also have well recognised national guidelines. Conclusions: Pathological examination of SLNs throughout Europe varies considerably and is not standardised. The European guidelines should focus on standardising examination. They should recommend techniques that identify metastases > 2 mm as a minimum standard. Uniform reporting of additional findings may also be important, because micrometastases and ITCs may in the future be shown to have clinical relevance.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Autriche</li><li>Belgique</li><li>Danemark</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Grèce</li><li>Hongrie</li><li>Irlande (pays)</li><li>Israël</li><li>Italie</li><li>Luxembourg (pays)</li><li>Pays-Bas</li><li>Portugal</li><li>Royaume-Uni</li><li>Suisse</li><li>Suède</li></country><region><li>Alsace (région administrative)</li><li>Berlin</li><li>Grand Est</li><li>Hovedstaden</li><li>Piémont</li><li>Provence-Alpes-Côte d'Azur</li><li>Province du Brabant flamand</li><li>Uusimaa</li><li>Vienne (Autriche)</li><li>Émilie-Romagne</li><li>Île-de-France</li></region><settlement><li>Berlin</li><li>Bologne</li><li>Copenhague</li><li>Helsinki</li><li>Louvain</li><li>Marseille</li><li>Paris</li><li>Strasbourg</li><li>Turin</li><li>Vienne (Autriche)</li></settlement><orgName><li>Université d'Helsinki</li><li>Université de Bologne</li></orgName></list><tree><country name="Hongrie"><noRegion><name sortKey="Cserni, G" sort="Cserni, G" uniqKey="Cserni G" first="G" last="Cserni">G. Cserni</name></noRegion><name sortKey="Fejes, G" sort="Fejes, G" uniqKey="Fejes G" first="G" last="Fejes">G. Fejes</name><name sortKey="Kulka, J" sort="Kulka, J" uniqKey="Kulka J" first="J" last="Kulka">J. Kulka</name></country><country name="Portugal"><noRegion><name sortKey="Amendoeira, I" sort="Amendoeira, I" uniqKey="Amendoeira I" first="I" last="Amendoeira">I. Amendoeira</name></noRegion><name sortKey="Lacerda, M" sort="Lacerda, M" uniqKey="Lacerda M" first="M" last="Lacerda">M. Lacerda</name></country><country name="Grèce"><noRegion><name sortKey="Apostolikas, N" sort="Apostolikas, N" uniqKey="Apostolikas N" first="N" last="Apostolikas">N. Apostolikas</name></noRegion></country><country name="France"><region name="Grand Est"><name sortKey="Bellocq, J P" sort="Bellocq, J P" uniqKey="Bellocq J" first="J P" last="Bellocq">J P Bellocq</name></region><name sortKey="Jacquemier, J" sort="Jacquemier, J" uniqKey="Jacquemier J" first="J" last="Jacquemier">J. Jacquemier</name><name sortKey="Sigal Zafrani, B" sort="Sigal Zafrani, B" uniqKey="Sigal Zafrani B" first="B" last="Sigal-Zafrani">B. Sigal-Zafrani</name></country><country name="Italie"><noRegion><name sortKey="Bianchi, S" sort="Bianchi, S" uniqKey="Bianchi S" first="S" last="Bianchi">S. Bianchi</name></noRegion><name sortKey="Eusebi, V" sort="Eusebi, V" uniqKey="Eusebi V" first="V" last="Eusebi">V. Eusebi</name><name sortKey="Sapino, A" sort="Sapino, A" uniqKey="Sapino A" first="A" last="Sapino">A. Sapino</name></country><country name="Allemagne"><noRegion><name sortKey="Boecker, W" sort="Boecker, W" uniqKey="Boecker W" first="W" last="Boecker">W. Boecker</name></noRegion><name sortKey="Decker, T" sort="Decker, T" uniqKey="Decker T" first="T" last="Decker">T. Decker</name></country><country name="Suisse"><noRegion><name sortKey="Borisch, B" sort="Borisch, B" uniqKey="Borisch B" first="B" last="Borisch">B. Borisch</name></noRegion></country><country name="Irlande (pays)"><noRegion><name sortKey="Connolly, C E" sort="Connolly, C E" uniqKey="Connolly C" first="C E" last="Connolly">C E Connolly</name></noRegion><name sortKey="Dervan, P" sort="Dervan, P" uniqKey="Dervan P" first="P" last="Dervan">P. Dervan</name></country><country name="Belgique"><region name="Province du Brabant flamand"><name sortKey="Drijkoningen, M" sort="Drijkoningen, M" uniqKey="Drijkoningen M" first="M" last="Drijkoningen">M. Drijkoningen</name></region><name sortKey="Faverly, D" sort="Faverly, D" uniqKey="Faverly D" first="D" last="Faverly">D. Faverly</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Ellis, I O" sort="Ellis, I O" uniqKey="Ellis I" first="I O" last="Ellis">I O Ellis</name></noRegion><name sortKey="Elston, C W" sort="Elston, C W" uniqKey="Elston C" first="C W" last="Elston">C W Elston</name><name sortKey="Wells, C A" sort="Wells, C A" uniqKey="Wells C" first="C A" last="Wells">C A Wells</name></country><country name="Finlande"><region name="Uusimaa"><name sortKey="Heikkila, P" sort="Heikkila, P" uniqKey="Heikkila P" first="P" last="Heikkila">P. Heikkila</name></region></country><country name="Pays-Bas"><noRegion><name sortKey="Holland, R" sort="Holland, R" uniqKey="Holland R" first="R" last="Holland">R. Holland</name></noRegion><name sortKey="Peterse, J L" sort="Peterse, J L" uniqKey="Peterse J" first="J L" last="Peterse">J L Peterse</name></country><country name="Israël"><noRegion><name sortKey="Kerner, H" sort="Kerner, H" uniqKey="Kerner H" first="H" last="Kerner">H. Kerner</name></noRegion></country><country name="Espagne"><noRegion><name sortKey="Martinez Penuela, J" sort="Martinez Penuela, J" uniqKey="Martinez Penuela J" first="J" last="Martinez-Penuela">J. Martinez-Penuela</name></noRegion><name sortKey="De Miguel, C" sort="De Miguel, C" uniqKey="De Miguel C" first="C" last="De Miguel">C. De Miguel</name><name sortKey="Zozaya, E" sort="Zozaya, E" uniqKey="Zozaya E" first="E" last="Zozaya">E. Zozaya</name></country><country name="Danemark"><region name="Hovedstaden"><name sortKey="Rank, F" sort="Rank, F" uniqKey="Rank F" first="F" last="Rank">F. Rank</name></region></country><country name="Autriche"><noRegion><name sortKey="Regitnig, P" sort="Regitnig, P" uniqKey="Regitnig P" first="P" last="Regitnig">P. Regitnig</name></noRegion><name sortKey="Reiner, A" sort="Reiner, A" uniqKey="Reiner A" first="A" last="Reiner">A. Reiner</name></country><country name="Luxembourg (pays)"><noRegion><name sortKey="Tanous, A M" sort="Tanous, A M" uniqKey="Tanous A" first="A M" last="Tanous">A M Tanous</name></noRegion></country><country name="Suède"><noRegion><name sortKey="Thorstenson, S" sort="Thorstenson, S" uniqKey="Thorstenson S" first="S" last="Thorstenson">S. Thorstenson</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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